This is the best-documented sound in the Muse catalogue and the one people get most wrong. It is worth doing properly, because once you understand it you can build it on almost any budget.
It is three amplifiers running at once. On Absolution in 2003, the bass signal was split to three Marshall DBS 7400 heads:
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Clean — compressed, round, tone rolled back rather than bright. This is the foundation, and it is doing more work than the dirt is.
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Electro-Harmonix Russian Big Muff Pi — the fuzz layer, sitting on top.
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Human Gear Animato — a Japanese boutique distortion. This is the "obscure Japanese pedal" the gear press keeps alluding to without ever naming.
On top of that, the riff was doubled on a Kyma synthesiser — a software synthesis system, not a bass synth pedal.
Chris described his own philosophy to Guitar World in 2020: he runs three separate amp rigs simultaneously, each with its own effects loop, keeping "the bottom end" clean on the primary amp while "any distortions are brought in on top of that." And: "Most of the time there's at least two amps going at once."
Two things you will read everywhere that are wrong. The Akai Deep Impact is not what makes the Hysteria sound — he owns one, but it is documented on Space Dementia, Plug In Baby, Apocalypse Please, I Belong to You and Unravelling, not Hysteria. And the SansAmp is the wrong era entirely; the Tech 21 units arrive around The Resistance in 2009, six years later.
And Uprising is not a synthesiser. This is the best fact in this entire article. The band wanted "a bass sound that almost sounded like a synth, without using synthesizers," having made "a conscious decision that the rhythm section had to be real." It is a real bass, distorted until it reads as a synth. Which means you need a fuzz pedal, not a synth pedal.
To replicate the Hysteria tone — layer one, clean and compressed:
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Darkglass Microtubes B3K V2 (RM999) — the blend control preserves your clean low end while layering grind on top. This is the Wolstenholme three-amp philosophy in a single pedal, and it is the most useful bass pedal in this article.
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EHX Battalion Bass Preamp & DI (RM769) — preamp, DI, drive and cab sim in one. Best value all-in-one.
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Darkglass Microtubes X (RM999) — multiband distortion with independent low/high crossover, which literally splits clean lows from dirty highs.
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Darkglass Hyper Luminal Compressor (RM1,299) — the compression half of layer one.
Layer two, the fuzz:
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EHX Nano Bass Big Muff Pi (RM415) — a Bass Muff with a dry blend. The most on-target item in this entire article for the price.
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Darkglass Duality Dual Fuzz Engine (RM849) — Darkglass describe it as "a gated sawtooth wave and a wicked high-octane grit." That gated sawtooth is the Hysteria voice almost exactly. Two engines, blendable. If you buy one pedal for this sound, buy this one.
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Tech 21 SansAmp Character Plus "English Muffy" (RM999) — a Big-Muff-voiced SansAmp; preamp and Muff in one box.
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ZVEX Vexter Mastotron (RM769) — documented on Chris's board via ZVEX's own artist page. Sub switch, gated, works properly on bass.
Layer three, the sawtooth synth:
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Source Audio C4 Synth (RM1,099) — the best-tracking synth pedal you can actually buy today, with a sawtooth-capable editor. This is the Hysteria synth layer.
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EHX Bass Mono Synth (RM669) — 11 voices, presets, one-knob simplicity. Plug in, find the saw, done. The easier sell and the better first pedal.
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Boss SY-1000 Guitar Synthesizer (RM5,600) — confirmed for guitar and bass with a dedicated bass mode. The no-compromise option.
Bass amps, if you are building the full three-layer idea: Darkglass Alpha Omega 900 (RM5,999), Darkglass Alpha-Omega 500 (RM3,899), Orange Terror Bass (RM3,299), Ampeg Venture V3 (RM2,873), Darkglass Alpha-Omega 200 (RM1,799). Cabs: Orange OBC115 (RM4,999), Orange OBC112 (RM2,099), Hartke 210XL V2 (RM2,155).